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Thorvald Nicolai Thiele (24 December 1838 – 26 September 1910) was a Danish astronomer, actuary and mathematician, most notable for his work in statistics, interpolation and the three-body problem. He was the first to propose a mathematical theory of Brownian motion. Thiele introduced the cumulants and (in Danish) the likelihood function; these contributions were not credited to Thiele by Ronald A. Fisher, who nevertheless named Thiele to his (short) list of the greatest statisticians of all time on the strength of Thiele's other contributions.

Thiele also was a founder and Mathematical Director of the Hafnia Insurance Company and led the founding of the Danish Society of Actuaries. It was through his insurance work that he came into contact with fellow mathematician Jørgen Pedersen Gram.

Thiele was the father of Holger Thiele.

Asteroids 843 Nicolaia (found by his son) and 1586 Thiele are named in his honour.