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Aleixo Garcia, also known in Spanish as Alejo García (d. 1525 Paraguay) was a Portuguese explorer and conquistador who explored the Rio de la Plata in service to Spain, and later the Paraguay and Bolivia.

He was possibly a member of the failed expedition of Juan Díaz de Solís, seeking to find a passage from the Atlantic to the Pacific Ocean. After reaching the mouths of the Uruguay and Paraná, it was apparent that the Rio de la Plata was not such a strait. At this point, de Solís was killed - on testimony of his crew - by cannibal Indians (variously identified as the Charrúa or Guaraní) and his lieutenants opted to return to Spain.