ArtieEven if that will happen, it may trigger new interesting opportunities - as mankind will have nowhere to go, it may start to create new generation ships, trying to colonize new planets, build new stations there and then try to retake the "old home" guerrilla-style. It may be easier than current battles, if Thargoids will be spread too thin and too wide (if there is/will be such mechanics). So even the end of the Bubble/Colonia may not mean the end of everything.
Now that the Thargoids are autonomous, it would make sense to give players the means to colonize star systems. Build another bubble elsewhere, and then have Thargoids attack that as well, rinse, repeat.
This would turn the entire galaxy into a playground for this war, ideally with no further manual intervention by FDev. Maybe that is the plan. Make the entire game an open-ended sandbox running on auto-pilot, where all further narrative is determined by player actions. This could also be the end of community goals. The Thargoid war is the new permanent community goal with real consequences, and any future CG would just be a distraction.